Synthesis of 4-Alkylamino-2-Triazolylquinazolines

Materials Science and Applied Chemistry 2017
Svetlana Marija Goliškina, Dace Cīrule, Ērika Bizdēna, Māris Turks

5-Alkylamino derivatives of tetrazolo[1,5-a]quinazoline were obtained with high regioselectivity in the reaction of 5-azidotetrazolo[1,5-a]quinazoline (formally, 2,4-diazidoquinazoline) with long chain alkylamines. The obtained 5-aminoquinazoline derivatives were used in a copper catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction to obtain series of 4-(alkylamino-2-(1,2,3-triazol-1-yl)quinazolines.

Atslēgas vārdi
4-Alkylamino-2-(1,2,3-triazol-1-yl)quinazoline, 5-azidotetrazolo[1,5-a]quinazoline.
DOI
10.1515/msac-2017-0009

Goliškina, S., Cīrule, D., Bizdēna, Ē., Turks, M. Synthesis of 4-Alkylamino-2-Triazolylquinazolines. Materials Science and Applied Chemistry, 2017, 34, 59.-62.lpp. ISSN 1407-7353. e-ISSN 2255-8713. Pieejams: doi:10.1515/msac-2017-0009

Publikācijas valoda
English (en)