Synthesis of Novel Betulin Conjugates
German-Polish-Baltic Conference on Organic Chemistry : Book of Abstracts 2018
Jevgeņija Lugiņina, Rūdolfs Beļaunieks, Andis Melderis, Reinis Vilšķērsts, Māris Turks

Betulin is an abundant naturally occurring triterpene, most commonly found in birch bark. Research shows that betulin and its derivatives possess wide spectrum of biological activities such as anti-HIV, anti-inflammatory, and anticancer properties. Use of betulin is limited by its low solubility in water. Therefore, structural modifications of betulin with new functional groups to improve both the bioactivity and solubility in water are being made.


Atslēgas vārdi
betulin, triterpenes, azoles
Hipersaite
https://www.chemie.uni-hamburg.de/veranstaltungen/6gpcoc/GBP_Abstracts.pdf

Lugiņina, J., Beļaunieks, R., Melderis, A., Vilšķērsts, R., Turks, M. Synthesis of Novel Betulin Conjugates. No: German-Polish-Baltic Conference on Organic Chemistry : Book of Abstracts, Vācija, Hamburg, 15.-19. maijs, 2018. Hamburg: Hamburger Print Service, 2018, 30.-30.lpp. ISBN 978-3-00-058883-9.

Publikācijas valoda
English (en)
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