RTU Research Outputs and Resources: Reasearch Staff

Structural Basis for Inhibition of the SARS-CoV-2 nsp16 by Substrate-Based Dual Site Inhibitors
(2024)

Gints Kalniņš, Laura Ruduša, Anna L. Bula, Diāna Zeļencova-Gopejenko, Olga Bobiļeva, Mihails Sisovs, Kaspars Tārs, Aigars Jirgensons, Kristaps Jaudzems, Raitis Bobrovs
Scientific article indexed in SCOPUS or WOS database

Structure of the Borrelia Burgdorferi ATP-Dependent Metalloprotease FtsH in Its Functionally Relevant Hexameric Form
(2024)

Kalvis Brangulis, Laura Ruduša, Ināra Akopjana, Kaspars Tārs
Scientific article indexed in SCOPUS or WOS database

Members of the Paralogous Gene Family 12 from the Lyme Disease Agent Borrelia Burgdorferi are Non-Specific DNA-Binding Proteins
(2024)

Kalvis Brangulis, Ināra Akopjana, Laura Ruduša, Sofija matisone, Diāna Zeļencova-Gopejenko, Shapla Bhattacharya, Jānis Bogaāns, Kaspars Tārs
Scientific article indexed in SCOPUS or WOS database

The Application of Adaptive Model Predictive Control for Fed-Batch Escherichia coli BL21 (DE3) Cultivation and Biosynthesis of Recombinant Proteins
(2023)

Konstantīns Dubencovs, Artūrs Šuleiko, Elīna Sīle, Ivars Petrovskis, Ināra Akopjana, Anastasija Šuleiko, Vytautas Galvanauskas, Kaspars Tārs, Juris Vanags
Scientific article indexed in SCOPUS or WOS database

Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX
(2023)

Janis Leitans, Andris Kazaks, Janis Bogans, Claudiu T. Supuran, Ināra Akopjana, Jekaterīna Ivanova, Raivis Žalubovskis, Kaspars Tārs
Scientific article indexed in SCOPUS or WOS database

Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect
(2023)

Jekaterīna Ivanova, Alessio Nocentini, Kaspars Tārs, Janis Leitans, Elviss Dvinskis, Andris Kazaks, Ilova Domračeva, Claudiu T. Supuran, Raivis Žalubovskis
Scientific article indexed in SCOPUS or WOS database

5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with Effective Carbonic Anhydrase Inhibitory Activity: Solution and Crystallographic Investigations
(2017)

Jekaterīna Ivanova, Agnese Balode, Raivis Žalubovskis, Janis Leitans, Andris Kazaks, Daniela Vullo, Kaspars Tārs, Claudiu T. Supuran
Scientific article indexed in SCOPUS or WOS database

3H-1,2-Benzoxathiepine 2,2-Dioxides: a New Class of Isoform-Selective Carbonic Anhydrase Inhibitors
(2017)

Aleksandrs Pustenko, Dmitrijs Stepanovs, Raivis Žalubovskis, Daniela Vullo, Andris Kazaks, Janis Leitans, Kaspars Tārs, Claudiu Supuran
Scientific article indexed in SCOPUS or WOS database

N-Substituted and Ring Opened Saccharin Derivatives Selectively Inhibit Transmembrane, Tumor-Associated Carbonic Anhydrases IX and XII
(2017)

Jekaterīna Ivanova, Fabrizio Carta, Daniela Vullo, Janis Leitans, Andris Kazaks, Kaspars Tārs, Raivis Žalubovskis, Claudiu T. Supuran
Scientific article indexed in SCOPUS or WOS database

CCDC 1526002: Experimental Crystal Structure Determination
(2017)

Aleksandrs Pustenko, Dmitrijs Stepanovs, Raivis Žalubovskis, Daniela Vullo, Andris Kazaks, Janis Leitans, Kaspars Tārs, Claudiu T. Supuran
Internet publication

Information about Author

Publications

Structural Basis for Inhibition of the SARS-CoV-2 nsp16 by Substrate-Based Dual Site Inhibitors
(2024)

Structure of the Borrelia Burgdorferi ATP-Dependent Metalloprotease FtsH in Its Functionally Relevant Hexameric Form
(2024)

Members of the Paralogous Gene Family 12 from the Lyme Disease Agent Borrelia Burgdorferi are Non-Specific DNA-Binding Proteins
(2024)

The Application of Adaptive Model Predictive Control for Fed-Batch Escherichia coli BL21 (DE3) Cultivation and Biosynthesis of Recombinant Proteins
(2023)

Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX
(2023)

Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect
(2023)

5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with Effective Carbonic Anhydrase Inhibitory Activity: Solution and Crystallographic Investigations
(2017)

3H-1,2-Benzoxathiepine 2,2-Dioxides: a New Class of Isoform-Selective Carbonic Anhydrase Inhibitors
(2017)

N-Substituted and Ring Opened Saccharin Derivatives Selectively Inhibit Transmembrane, Tumor-Associated Carbonic Anhydrases IX and XII
(2017)

CCDC 1526002: Experimental Crystal Structure Determination
(2017)

Information about Author

Publications

Structural Basis for Inhibition of the SARS-CoV-2 nsp16 by Substrate-Based Dual Site Inhibitors (2024)

Structure of the Borrelia Burgdorferi ATP-Dependent Metalloprotease FtsH in Its Functionally Relevant Hexameric Form (2024)

Members of the Paralogous Gene Family 12 from the Lyme Disease Agent Borrelia Burgdorferi are Non-Specific DNA-Binding Proteins (2024)

The Application of Adaptive Model Predictive Control for Fed-Batch Escherichia coli BL21 (DE3) Cultivation and Biosynthesis of Recombinant Proteins (2023)

Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX (2023)

Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect (2023)

5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with Effective Carbonic Anhydrase Inhibitory Activity: Solution and Crystallographic Investigations (2017)

3H-1,2-Benzoxathiepine 2,2-Dioxides: a New Class of Isoform-Selective Carbonic Anhydrase Inhibitors (2017)

N-Substituted and Ring Opened Saccharin Derivatives Selectively Inhibit Transmembrane, Tumor-Associated Carbonic Anhydrases IX and XII (2017)

CCDC 1526002: Experimental Crystal Structure Determination (2017)

Structural Basis for Inhibition of the SARS-CoV-2 nsp16 by Substrate-Based Dual Site Inhibitors
(2024)

Structure of the Borrelia Burgdorferi ATP-Dependent Metalloprotease FtsH in Its Functionally Relevant Hexameric Form
(2024)

Members of the Paralogous Gene Family 12 from the Lyme Disease Agent Borrelia Burgdorferi are Non-Specific DNA-Binding Proteins
(2024)

The Application of Adaptive Model Predictive Control for Fed-Batch Escherichia coli BL21 (DE3) Cultivation and Biosynthesis of Recombinant Proteins
(2023)

Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX
(2023)

Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect
(2023)

5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with Effective Carbonic Anhydrase Inhibitory Activity: Solution and Crystallographic Investigations
(2017)

3H-1,2-Benzoxathiepine 2,2-Dioxides: a New Class of Isoform-Selective Carbonic Anhydrase Inhibitors
(2017)

N-Substituted and Ring Opened Saccharin Derivatives Selectively Inhibit Transmembrane, Tumor-Associated Carbonic Anhydrases IX and XII
(2017)

CCDC 1526002: Experimental Crystal Structure Determination
(2017)