The Effect of Pore Forming Agent Particle Size on the Porosity, Microstructure and In Vitro Studies of Hydroxyapatite Ceramics

Key Engineering Materials 2012
Vita Šteinberga, Jānis Ločs, Daina Vempere, Līga Bērziņa-Cimdiņa

In situ viscous mass foaming with ammonium bicarbonate (NH4HCO3) as foaming agent was used for the preparation of porous hydroxyapatite ceramics. Three different particle fractions (100-300 μm, 300-500 μm, 500-1000 μm) of NH4HCO3 were used in order to evaluate the particle size effect on the ceramic microstructure. Foamed and dried green bodies were sintered at 1150oC. The porosity and microstructure of ceramics were determined with Archimedes method and scanning electron microscopy. As the NH4HCO3 particle fraction was decrease from 100-300 μm to 500-1000 μm, the open porosity increased from 42 to 54 %. In situ viscous mass foaming leads to the interconnected pore channels with wide pore size range (10-600 μm). In the present work cytotoxicity of obtained porous HA ceramics and fibroblast cell viability was investigated.

Keywords
porous ceramics, particle size, mass foaming, porosity, cytotoxycity
DOI
10.4028/www.scientific.net/KEM.493-494.277
Hyperlink
http://www.scientific.net/KEM.493-494.277

Zālīte, V., Ločs, J., Vempere, D., Bērziņa-Cimdiņa, L. The Effect of Pore Forming Agent Particle Size on the Porosity, Microstructure and In Vitro Studies of Hydroxyapatite Ceramics. Key Engineering Materials, 2012, Vol.493-494, pp.277-280. ISSN 1013-9826. Available from: doi:10.4028/www.scientific.net/KEM.493-494.277

Publication language
English (en)