α-Tricalcium Phosphate Hydration to Calcium Deficient Hydroxyapatite in Calcium Phosphate Cements
European Cells and Materials 2012
Zilgma Irbe, Natālija Borodajenko, Jānis Ločs, Līga Bērziņa-Cimdiņa

In this work cements based on α-tricalcium phosphate (α-TCP) are investigated. Results show that initial pH of the liquid phase for α-TCP based cements significantly influences crystal morphology and setting reaction. FTIR results show that CDHA formation process continues for several days, even after all α-TCP is hydrated. CDHA phase formed after hydration of α-TCP lacks characteristic [OH] groups during first 2 days. In vitro tests using osteoblast cell line (MG63) show differences between cements (after reactions in cements are complete). In vivo tests in rabbits show good compatibility and complete healing for all cements tested (initial liquid phase pH 8, 7 und 6).


Keywords
Biomaterials, bone cement, calcium phosphate cements, calcium phosphates
Hyperlink
http://www.ecmjournal.org/journal/supplements/vol023supp05/pdf/Vol23supp05a43.pdf

Irbe, Z., Borodajenko, N., Ločs, J., Bērziņa-Cimdiņa, L. α-Tricalcium Phosphate Hydration to Calcium Deficient Hydroxyapatite in Calcium Phosphate Cements. European Cells and Materials, 2012, Vol.23. Suppl.5, pp.43-43. ISSN 1473-2262.

Publication language
English (en)
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