Synthesis and Characterization of Magnesium-Substituted Hydroxyapatite
Second International Conference for Students and Young Scientists on Materials Processing Science : Programme and Book of Manuscripts 2012
Līga Stīpniece, Kristīne Šalma-Ancāne, Natālija Borodajenko, Dmitrijs Jakovļevs, Līga Bērziņa-Cimdiņa

The preparation of synthetic magnesium-substituted hydroxyapatite (Mg-HAp) is of great interest for developing of artificial bone substitutes, which are characterised by high bioactivity. Magnesium (Mg) is one of the most important bivalent ions associated with biological apatite. Enamel, dentin and bone contain, respectively, 0.44, 1.23, and 0.72 weight% of Mg. In this work were studied phase and chemical composition, morphology, and thermal stability of Mg-HAp products which were synthesized using wet chemical precipitation of homogenous suspension prepared from Ca(OH)2/Mg(OH)2 suspension, and H3PO4 solution. The starting slurry of Mg(OH)2/Ca(OH)2 were prepared dissolving (100-x) weight% CaO and x weight% MgO (where x in range of 0.1-20.0 weight%) powder mixture in distilled water, and milled in the planetary ball mill to obtain a homogeneous suspension. The influence of different amounts of Mg substitution on physicochemical properties of as-synthesized and sintered Mg-HAp powders was evaluated by the following analytical techniques: differential thermal analysis (DTA), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR), field emission electron microscopy/energy dispersive X-ray spectroscopy (FE-SEM/EDX). Through phase and chemical composition analysis was determined that the as-prepared powders were Mg-HAp products with different amount of Mg (0.21-4.72 weight%) incorporated into HAp structure. Mg concentration of Mg-HAp products is increasing by increasing the MgO content in Ca(OH)2/Mg(OH)2 suspension. It has been evidenced that substitution of Mg in the HAp induces modifications in as-synthesized powder particle morphology, and thermal stability. Thermal stability of Mg-HAp samples decreased while increasing the Mg content.


Keywords
hydroxyapatite, magnesium, wet chemical precipitation

Stīpniece, L., Šalma-Ancāne, K., Borodajenko, N., Jakovļevs, D., Bērziņa-Cimdiņa, L. Synthesis and Characterization of Magnesium-Substituted Hydroxyapatite. In: Second International Conference for Students and Young Scientists on Materials Processing Science : Programme and Book of Manuscripts, Georgia, Tbilisi, 10-13 October, 2012. Tbilisi: Georgian Technical University, 2012, pp.114-119.

Publication language
English (en)
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