Improvement of Calcium Phosphate Cement Cohesion Using Liquid Phase Additives
Symposium "Bioceramics and Cells for Reinforcements of Bone": Book of Abstracts 2012
Zilgma Irbe, Daina Vempere, Dagnija Loča, Līga Bērziņa-Cimdiņa

It has been described in scientific literature that the presence of polymeric additives in cement liquid phase can improve cohesion of calcium phosphate cements [1-3]. In this work influence of liquid phase composition, including water-soluble polymers, on calcium phosphate cement cohesion and setting time was examined. Several water soluble polymers (sodium alginate, polyvinyl alcohol, carboxymethyl cellulose sodium salt, hydroxyethyl cellulose) were added to liquid phase of the cement. The solid phase of the cement was α-tricalcium phosphate. Mixtures of sodium phosphate salts were added to either solid or liquid phase of the cement to ensure setting. The cement cohesion was evaluated both visually and by the weight of particles released from cement surface. It was found that cement cohesion strongly correlated with cement setting time. Cements that had the fastest setting time exhibited the best cohesive properties – fewer particles were released from the cement surface. The presence of sodium alginate and carboxymethyl cellulose additives did not decisively improve cohesion. Polyvinyl alcohol improved cement cohesion and also shortened setting time. Hydroxyethyl cellulose improved cement cohesion if basic phosphate salt mixture was used as setting agent. Cohesion was also improved, if the mixture of calcium phosphate salts was added to liquid phase instead of solid phase.


Keywords
biomaterials, calcium phosphates, bone cement, calcium phosphate bone cement

Irbe, Z., Vempere, D., Loča, D., Bērziņa-Cimdiņa, L. Improvement of Calcium Phosphate Cement Cohesion Using Liquid Phase Additives. In: Symposium "Bioceramics and Cells for Reinforcements of Bone": Book of Abstracts, Latvia, Rīga, 18-20 October, 2012. Riga: Riga Stradins University, 2012, pp.43-43. ISBN 978-9984-793-18-4.

Publication language
English (en)
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