Novel Palladium-Catalyzed Domino Reaction of 2-Methylindoles with 2-Iodobenzyl Bromide

Chemistry of Heterocyclic Compounds 2016
E. Ābele, Sergejs Beļakovs, T. Beresneva, L. Golomba, R. Ābele

A novel palladium-catalyzed domino reaction of 2-methylindoles with 2-iodobenzyl bromide in the system Pd(OAc)2/Xantphos/t-BuOK/PhMe leading to indole-fused tricyclo[7,3,1,02,7]trideca-2(7),3,5-triene ring system is presented. Pd-catalyzed reaction of 2-methylindole with 5-bromo-6-bromomethylbenzo[1,3]dioxole afforded 3,3-bis(6-bromobenzo[1,3]dioxol-5-ylmethyl)-2-methyl-3H-indole.

Atslēgas vārdi
domino reaction, 2-methylindoles, 2-iodobenzyl bromide
DOI
10.1007/s10593-016-1846-2
Hipersaite
http://hgs.osi.lv/index.php/hgs/article/view/2768

Ābele, E., Beļakovs, S., Beresneva, T., Golomba, L., Ābele, R. Novel Palladium-Catalyzed Domino Reaction of 2-Methylindoles with 2-Iodobenzyl Bromide. Chemistry of Heterocyclic Compounds, 2016, Vol.52, No.2, 140.-142.lpp. ISSN 0009-3122. e-ISSN 1573-8353. Pieejams: doi:10.1007/s10593-016-1846-2

Publikācijas valoda
English (en)