Synthesis of Triazole-Functionalized Tetrahydroindazolones by 1,3-dipolar Cycloadditions between Azides and Alkynes
Tetrahedron Letters
2009
Inta Strakova,
Māris Turks,
Andris Strakovs
7-Azido-tetrahydroindazolones undergo efficient copper-catalyzed Huisgen 1,3-dipolar cycloaddition
reactions with various alkynes leading to a straightforward synthesis of triazole-functionalized tetrahydroindazolones.
The latter are interesting molecular platforms in terms of medicinal chemistry.
Atslēgas vārdi
tetrahydroindazolones, azides, triazoles, Huisgen 1,3-dipolar cycloaddition
DOI
10.1016/j.tetlet.2009.04.009
Hipersaite
http://www.sciencedirect.com/science/article/pii/S0040403909008107
Strakova, I., Turks, M., Strakovs, A. Synthesis of Triazole-Functionalized Tetrahydroindazolones by 1,3-dipolar Cycloadditions between Azides and Alkynes. Tetrahedron Letters, 2009, Vol.50, Iss.25, 3046.-3049.lpp. ISSN 0040-4039. Pieejams: doi:10.1016/j.tetlet.2009.04.009
Publikācijas valoda
English (en)