Porous Bioceramic Bone Grafts for Drug Immobilization

European Cells and Materials 2010
Vita Šteinberga, Dagnija Loča, Jānis Ločs, Līga Bērziņa-Cimdiņa

In this study an attempt was made to prepare the porous hydroxyapatite scaffolds with sufficient mechanical strength, pore size and sustained drug release. Hydroxyapatite was mixed with an organic additive (polyol) to obtain a highly viscous/plastic mixture. As pore foaming agent H4NHCO3 was added to the plastic mass. Lidocaine hydrochloride was used as a model drug for DDS preparation.

Keywords
porous bioceramic, hydroxyapatite, drug delivery systems, lidocaine, PVA coating
Hyperlink
http://www.ecmjournal.org/journal/supplements/vol020supp03/pdf/v020supp03a280.pdf

Zālīte, V., Loča, D., Ločs, J., Bērziņa-Cimdiņa, L. Porous Bioceramic Bone Grafts for Drug Immobilization. European Cells and Materials, 2010, Vol.20, Suppl.3, pp.280-280. e-ISSN 1473-2262.

Publication language
English (en)