RTU Research Outputs and Resources: Reasearch Staff

Information about Author

Name, Surname:

Aigars Jirgensons

Department:

(32300) Ķīmijas un ķīmijas tehnoloģijas institūts

Scientific Degree:

Doktors

E-mail:

Aigars.Jirgensons(at)rtu.lv

Publications

132 items found, displaying 11 to 20.

Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials
(2022)

Raitis Bobrovs, Emīls Edgars Basens, Laura Drunka, Iveta Kanepe, Sofija matisone, Karlis Kristofers Velins, Victor Andrianov, Gundars Leitis, Diāna Zeļencova-Gopejenko, Dace Rasiņa, Aigars Jirgensons, Kristaps Jaudzems
Scientific article indexed in SCOPUS or WOS database

Functionalization of Tetrazoles Bearing the Electrochemically Cleavable 1 N-(6-Methylpyridyl-2-methyl) Protecting Group
(2022)

Konstantinos Grammatoglou, Madara Dārziņa, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Functionalization of 1 N-Protected Tetrazoles by Deprotonation with the Turbo Grignard Reagent
(2022)

Konstantinos Grammatoglou, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Convergent Biomimetic Semisynthesis of Disesquiterpenoid Rumphellolide J
(2022)

Georgijs Stakanovs, Sergejs Beļakovs, Aigars Jirgensons, Dace Rasiņa
Scientific article indexed in SCOPUS or WOS database

Peptidic Boronic Acids are Potent Cell-Permeable Inhibitors of the Malaria Parasite Egress Serine Protease SUB1
(2021)

Elīna Līdumniece, C Withers-Martinez, F Hackett, C.R Collins, AJ Perrin, K Koussis, C Bisson, M.J Blackman, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Synthesis of Indazoles from 2-Formylphenylboronic Acids
(2021)

Vitalii Solomin, A Šeins, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate
(2021)

Olga Bobiļeva, R Bobrovs, I Kaņepe, L Patetko, G Kalniņš, M Šišovs, A.L Bula, S Grīnberga, M.R Borodušķis, A Ramata-Stunda, N Rostoks, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Torii-Type Electrosynthesis of α,β-Unsaturated Esters from Furfurylated Ethylene Glycols and Amino Alcohols
(2021)

Madara Dārziņa, Anna Lielpētere, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening
(2021)

R Bobrovs, I Kaņepe, N Narvaiss, L Patetko, G Kalniņš, M Sisovs, A.L Bula, S Grīnberga, M Borodušķis, A Ramata-Stunda, N Rostoks, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

2-Aminoquinazolines by Chan-Evans-Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids
(2020)

V.V. Solomin, A. Seins, Aigars Jirgensons
Scientific article indexed in SCOPUS or WOS database

Information about Author

Publications

Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials
(2022)

Functionalization of Tetrazoles Bearing the Electrochemically Cleavable 1 N-(6-Methylpyridyl-2-methyl) Protecting Group
(2022)

Functionalization of 1 N-Protected Tetrazoles by Deprotonation with the Turbo Grignard Reagent
(2022)

Convergent Biomimetic Semisynthesis of Disesquiterpenoid Rumphellolide J
(2022)

Peptidic Boronic Acids are Potent Cell-Permeable Inhibitors of the Malaria Parasite Egress Serine Protease SUB1
(2021)

Synthesis of Indazoles from 2-Formylphenylboronic Acids
(2021)

Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate
(2021)

Torii-Type Electrosynthesis of α,β-Unsaturated Esters from Furfurylated Ethylene Glycols and Amino Alcohols
(2021)

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening
(2021)

2-Aminoquinazolines by Chan-Evans-Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids
(2020)

Supervised Dissertations

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors
(2023)

Development of New Synthetic Methods based on Electrochemical Oxidation of Stannylmethylethers and Furan Derivatives
(2023)

Development of Malarial Enzyme Inhibitors
(2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase
(2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols
(2020)

Electrophile-Induced Cyclopropane Reactions with Nucleophiles
(2018)

Development of Malarial Aspartic Protease Inhibitors
(2016)

Development of Malarial Protease PfSUB1 Inhibitors
(2014)

C-Heteroatom Bond Formation In Lewis Acid Catalysed Allylic Substitution Reaction
(2013)

Projects

Atbalsts RTU doktora studiju īstenošanai - 2
Izglītība

Methods of critical infrastructure control
Enerģētika

Information about Author

Publications

Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials (2022)

Functionalization of Tetrazoles Bearing the Electrochemically Cleavable 1 N-(6-Methylpyridyl-2-methyl) Protecting Group (2022)

Functionalization of 1 N-Protected Tetrazoles by Deprotonation with the Turbo Grignard Reagent (2022)

Convergent Biomimetic Semisynthesis of Disesquiterpenoid Rumphellolide J (2022)

Peptidic Boronic Acids are Potent Cell-Permeable Inhibitors of the Malaria Parasite Egress Serine Protease SUB1 (2021)

Synthesis of Indazoles from 2-Formylphenylboronic Acids (2021)

Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate (2021)

Torii-Type Electrosynthesis of α,β-Unsaturated Esters from Furfurylated Ethylene Glycols and Amino Alcohols (2021)

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening (2021)

2-Aminoquinazolines by Chan-Evans-Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids (2020)

Supervised Dissertations

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors (2023)

Development of New Synthetic Methods based on Electrochemical Oxidation of Stannylmethylethers and Furan Derivatives (2023)

Development of Malarial Enzyme Inhibitors (2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase (2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols (2020)

Electrophile-Induced Cyclopropane Reactions with Nucleophiles (2018)

Development of Malarial Aspartic Protease Inhibitors (2016)

Development of Malarial Protease PfSUB1 Inhibitors (2014)

C-Heteroatom Bond Formation In Lewis Acid Catalysed Allylic Substitution Reaction (2013)

Projects

Atbalsts RTU doktora studiju īstenošanai - 2 Izglītība

Methods of critical infrastructure control Enerģētika

Exploring Aspartic Protease Inhibitor Binding to Design Selective Antimalarials
(2022)

Functionalization of Tetrazoles Bearing the Electrochemically Cleavable 1 N-(6-Methylpyridyl-2-methyl) Protecting Group
(2022)

Functionalization of 1 N-Protected Tetrazoles by Deprotonation with the Turbo Grignard Reagent
(2022)

Convergent Biomimetic Semisynthesis of Disesquiterpenoid Rumphellolide J
(2022)

Peptidic Boronic Acids are Potent Cell-Permeable Inhibitors of the Malaria Parasite Egress Serine Protease SUB1
(2021)

Synthesis of Indazoles from 2-Formylphenylboronic Acids
(2021)

Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate
(2021)

Torii-Type Electrosynthesis of α,β-Unsaturated Esters from Furfurylated Ethylene Glycols and Amino Alcohols
(2021)

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening
(2021)

2-Aminoquinazolines by Chan-Evans-Lam Coupling of Guanidines with (2-Formylphenyl)boronic Acids
(2020)

Development of Scalable Synthesis for Selected Serine Protease uPA Inhibitors
(2023)

Development of New Synthetic Methods based on Electrochemical Oxidation of Stannylmethylethers and Furan Derivatives
(2023)

Development of Malarial Enzyme Inhibitors
(2023)

The Development of New Methods for the Synthesis of PLP-Dependent Enzyme Inhibitors and Exploring Covalent Inhibition Potential of Bacterial Enzyme O-Acetylserine Sulfhydrylase
(2023)

New Methods for the Synthesis and C–H Functionalization of Amino Alcohols
(2020)

Electrophile-Induced Cyclopropane Reactions with Nucleophiles
(2018)

Development of Malarial Aspartic Protease Inhibitors
(2016)

Development of Malarial Protease PfSUB1 Inhibitors
(2014)

C-Heteroatom Bond Formation In Lewis Acid Catalysed Allylic Substitution Reaction
(2013)

Atbalsts RTU doktora studiju īstenošanai - 2
Izglītība

Methods of critical infrastructure control
Enerģētika